isishwankathelo

IKomiti yePotfoliyo yezeMpilo ibize inkomfa yevidiyo ekwi-intanethi eza kunikwa amagqabantshintshi nguMphathiswa kunye neSebe lezeMpilo malunga nesicwangciso-qhinga sokukhupha isitofu sokugonya i-COVID-19 kunye neminye imiba yokhathalelo lwempilo enxulumene nobhubhane.

UMphathiswa wezeMpilo ubhengeze ukuba uMzantsi Afrika uza kufumana iidosi zokugonya ezisisigidi esi-1 kwiSerum Institute of India ngoJanuwari 2021 kunye nezinye iidosi ezingama-500 000 ngoFebruwari 2021.

UMphathiswa uthathele iKomiti ngeengqwalasela malunga nokukhutshwa kwesitofu sokugonya. Isicwangciso sesokuba abantu abazizigidi ezingama-40 bagonywe kwiinyanga ezili-12 – ama-6 300 amayeza asisigxina, betofa ukuya kutsho kuma-50 abantu ngosuku. UMphathiswa uthe ekuphela kwendlela yokhuseleko [kwi-Covid-19] iza kuvela kwinkqubo yogonyo, kwaye ubuncinci be-67% yabemi boMzantsi Afrika kufuneka bafumane isitofu sokugonya i-Covid-19 ukuze umjikelo wosulelo ukuya yaphulwe. Kwagxininiswa ukuba ngurhulumente kuphela oza kuba ngumthengi wesitofu sokugonya. I-SA kulindeleke ukuba ifumane i-Covax yezitofu zokugonya ngo-Epreli kodwa kukwakho iingxoxo nabavelisi bamachiza. Nangona uNondyebo eza kuthwala “umthwalo omkhulu” wokufumana isitofu sokugonya, amanye amanyathelo amabini enkxaso-mali aya kuphandwa: ukucela izikimu zonyango zabucala ukuba zixhase ugonyo kunye nokucela abaxhasi kunye neshishini ukuba benze iminikelo.

Le nkcazo-ntetho yachaza imiba enxulumene ne-epidemiology kunye nokuhlolwa kwezitofu zokugonya; iindlela kumatyala amatsha, ukulaliswa esibhedlele kunye nokufa; inkqubo-sikhokelo yokuphunyezwa kwesitofu sokugonya; imithetho-siseko engundoqo yokuqaliswa; ukuchongwa nokubekwa phambili kwabantu abathile ekujoliswe kubo; indlela yokuqaliswa ngezigaba yesitofu sokugonya; imiba yolawulo; ukuhanjiswa kwesitofu kunye nemiba yokhuseleko; iimfuno zobutyebi; ukhuseleko, ukusebenza kakuhle, ukuthatha, kunye nethamo lesibini; unxibelelwano noluntu, isikhokelo noqeqesho lwabachaphazelekayo; iindima noxanduva olwahlukeneyo lweSebe lezeMpilo leSizwe kunye namaphondo; kwaye okokugqibela uhlahlo lwabiwo-mali olululo lwesicwangciso-qhinga sokuqalisa.

Ngokumalunga nokuqhambuka kwesibini kwe-Covid-19 eMzantsi Afrika, uMphathiswa uxele ukuba kukho imfuneko enkulu yeebhedi esibhedlele kunye neoksijini, nto leyo enyanzelisa ukuba “kuvuswe” iibhedi ebezikade zingasebenzi.

Kumaphondo afana neMpuma Koloni kunye neNtshona Koloni, amanani abosulelekileyo ngoku agqithile kwinto ebeyincopho yelanga lokuqala ngo-2020, ngelixa KwaZulu-Natal phantse inani eliphindwe kabini lezigulane ezilaliswe esibhedlele ngo-2020.

Amalungu eKomiti abuze imibuzo ebukhali malunga, phakathi kwezinye izinto, ukungangqinelani, kunye nokucingelwa ukuba akuchaneki, iinkcukacha-manani ezisemthethweni ingakumbi phakathi kwamaphondo.

Amalungu avakalise inkxalabo egqithisileyo malunga nokuba ngaba unyango oluyimfuneko luyabonelelwa kuzo zonke izigulana ukuze kwandiswe izinga lokusinda. Kwakukho inkxalabo malunga nezinga eliphezulu lokusweleka kwabaguli abangosulelwanga yi-COVID19 - kwathiwa "kukho abantu abafayo ekungafanelanga bafe". Amalungu athi "aphazamiseke kakhulu" yimeko ekwinqanaba lentlekele. Amalungu abuze malunga nokufumaneka kweebhedi kunye neoksijini. Umphathiswa wacelwa ukuba achaze ukuba kutheni izibhedlele zaseMzantsi Afrika bezingekalungiswa nangona ilusuku lwama-287 lokuvalwa komsebenzi kwaye kutheni izibhedlele zasendle ziye zayekiswa ukusebenza ngenxa yolindelo lwamaza angakumbi. Kwathiwa lo gama urhulumente woMzantsi Afrika echitha ixesha lakhe ngemigaqo ephantsi kwenqanaba lesihlanu, amanye amazwe aye alungiselela amacandelo awo ezempilo kwaye afumana amayeza okugonya. Amalungu akakhange urhulumente agxininise indima yabemi ekuthatheni amanyathelo othintelo (ukunxiba iimaski, ukucoca, nokunye okunjalo) xa kugxininiswa ekufumaneni amayeza okugonya. Ke ngeli lixa abemi bebambe isiphelo sesivumelwano, urhulumente akakasikhuselanga isitofu kwaye iSebe lezeMpilo leSizwe “lalihlehla”.

Amalungu avakalise ngamxhelo mnye inkxalabo yawo malunga nolwazi olungachananga kunye nokungabikho kolwazi olunikwa uluntu. Isebe liye labongozwa ukuba liphinde lithathele ingqalelo izicwangciso zalo zonxibelelwano ngokubhekiselele kungekuphela nje isitofu kodwa liqinisekise ukuba abantu bayafika kwangethuba ukuya ezibhedlele kwaye babe neenkcukacha malunga nendlela yokuzikhathalela emva kokukhutshwa. Kwakukho inkxalabo yokuba amanye amaLungu akufumanisa kunzima ukubamba uMphathiswa, uSekela Mphathiswa kunye namaqumrhu abalulekileyo eSebe awayephendula kwiKomiti. Amalungu avakalise inkxalabo malunga nethuba lorhwaphilizo malunga nokuthengwa nokuqaliswa kwesitofu sokugonya.

Amalungu abhenele ukuba kucace ukuba imeko ephantsi iza kuqwalaselwa njani, kunye nokuba unyango olufanelekileyo luya kubonelelwa njani kwiiveki ezizayo.

Kwakhona kwavakaliswa inkxalabo yokuba kubonakala ngathi ezinye izitofu zokugonya azifikeleleki kuMzantsi Afrika ukanti urhulumente ubeke phambili ukuhlangulwa kwe-SA Airways. Amaxhala angakumbi aye asasazwa ukuba ingaba ukuthengwa okungundoqo kwezitofu zokugonya kungakhokelela kwinkqubo “ecothayo” ngakumbi ukuba urhulumente akanawo la mava kwaye ukuba sembindini kuthintele abanye abadlali ekuthatheni inxaxheba ekunikezelweni. Kwagxininiswa ukuba kufuneka kubekho isicwangciso esidityanisiweyo nesibanzi sesitofu sokugonya esinokuthi senziwe esidlangalaleni.

Amalungu abuza ukuba kwenzeka ntoni na kwizithuba zomda, ingaba izitofu zokugonya zisisinyanzelo, zihambe njani izitofu ngenxa yohlobo olutsha lwentsholongwane echongiweyo, indima yoncedo lwezonyango lwabucala, iinkcukacha ezijikeleze xa unxibelelwano lwamazwe amabini kunye nabavelisi bogonyo lwenzeka, ukubekwa. yabafundi abasaqeqeshwayo kunye noogqirha abadla umhlala-phantsi ukuncedisa ukunqongophala kwabasebenzi, indima yamaphondo ekukhutshweni kwesitofu sokugonya, ukhathalelo lokuthomalalisa kunye nentsebenziswano neeyunivesithi.

Kwakukho imibuzo malunga nokusetyenziswa kwe-ivermectin kunye nokusebenza kwayo ekunciphiseni ukuziphatha kunye nokuba ngaba i-SA Health Products Regulatory Authority yenze uphando olwaneleyo malunga noku.

Amanye amaLungu abize intlanganiso noMphathiswa wezeziMali ukuze acacise iinkcukacha ezithile zemali ezinxulumene nesicwangciso sokuqaliswa, ngaphandle kwegalelo lakhe iinkcukacha zahlala zimfiliba.

IKomiti kunye noMphathiswa bavumelene ngemfuneko yokulawula iintlanganiso phakathi kwamaqela ukuze kuqinisekiswe ukuba amaLungu ahlaziywa rhoqo ukuze kuqinisekiswe ukuba wonke umntu ukwikhasi elinye ngakumbi njengoko iKomiti yayiliqabane kwinkqubo.

Isishwankathelo sinikezelwe ngu IQela eliPhonononge iPalamente

IKomiti yePotfoliyo yezeMpilo idibene kwiqonga elibonakalayo kwingcaciso yoMphathiswa wezeMpilo kunye neeNtloko zamaSebe ezeMpilo eMpuma Koloni naseNtshona Koloni ngenkqubela eyenziwe ngamaphondo ukulwa nobhubhane we-Covid-19 nasekulungiseleleni. ukuqaliswa kogonyo lwe-Covid-19.

ISebe lezeMpilo eMpuma Koloni lichazele iKomiti malunga namatyala e-Covid-19 ephondweni, ubukho bebhedi, ukwamkelwa kweCovid-19, ukubonelelwa ngeoksijini, uvavanyo lwe-Covid-19, izikolo zolwaluko, ukuvavanywa kwezidumbu, ubukho bamayeza kunye nezixhobo zokuzikhusela. ngokunjalo nesicwangciso sokunatyiswa kogonyo eMpuma Koloni. Ukuqala kosulelo kwiphondo kunyuke kakhulu embindini kaDisemba ka-2020, kodwa ukonyuka kosulelo kwenzeke kwizithili ezahlukeneyo ngamaxesha ahlukeneyo kwaye ke iliza lesibini lalithatha ixesha elide kuneliza lokuqala. Lo bhubhani ube nefuthe elibi kubasebenzi bezempilo kwiphondo nge-9249 abavavanywa benesifo kwaye abali-161 babulawa yintsholongwane. I-3.7 yezigidi zabantu eMpuma Koloni bebeza kugonyelwa i-Covid-19, kuqalwa ngabasebenzi abangama-200 000 bezempilo kunye nabanye abasebenzi abanxulumene noko.

Amalungu eKomiti abuze ukuba yintoni na enokwenziwa ngokwembono yesizwe ukunceda iSebe nokuphucula umgangatho wobomi eMpuma Koloni. Yayingoobani oonobangela bemingeni kwaye yintoni anokuyenza urhulumente kazwelonke ukuncedisa? Leliphi inani eliqhelekileyo lokubhubha kwabantu eMpuma Koloni xa lithelekiswa nenani ngexesha lobhubhane? Ilungu libuze ukuba ngaba uphando lwenziwe nge-Ivermectin, ngoku ebizwa ngokuba liyeza lonyango lwezilwanyana, elinikwe abaguli baseMpuma Koloni abosulelwe yi-Covid-19. Omnye ubuze ukuba iphondo lenze ntoni ukuze baphendule abo banike i-Ivermectin ebantwini ngaphandle kwemvume ye-South African Health Products Regulatory Authority (SAPHRA).

Amalungu ebexhalabile ngenxa yenani lezithuba ezingenabantu eMpuma Koloni, nkqu neSebe lezeMpilo lineBambela leNtloko yeSebe. Njengoko iphondo belingekabinaso isicwangciso sokuqaliswa kogonyo, iKomiti ingasifumana nini isicwangciso esibanzi? Ngaba ukufakelwa kweoksijini eninzi okucetyiweyo kuqale nge-11 kaJanuwari 2021? Ngaba bekukho imfuneko yezibhedlele ezitsha kwizithili ezithathu ezifikelele kumthamo omkhulu weebhedi okanye iiwadi zinokutshintshwa zibe ziiwadi ze-Covid-19? Ngaba uVavanyo lwe-Antigen olukhawulezileyo, olucetyiswa nguMbutho wezeMpilo weHlabathi ukuchonga iimeko kwiindawo ezinomlinganiselo ophezulu wosulelo, luza kusetyenziselwa iinjongo zokuxilonga kwaye yayiyintoni inzuzo yoko?

Amalungu aqaphele ukuba uluntu lwalungazi ukuba mabenze ntoni xa abantu begula yi-Covid. Zeziphi izicwangciso iMpuma Koloni enazo zokulungisa lo nto? Ingaba abasebenzi bokhathalelo lwempilo basekuhlaleni baya kunikwa nini iikhontrakthi ezisisigxina ukuze bancedise ekulweni ubhubhane? Kwakutheni ukuze isithili saseJoe Gqabi sibe nokwanda kwamatyala amatsha xa incopho idlulile? Kwakutheni ukuze izigulane ezine-Covid-19 zixutywe nezigulana ze-TB kwiSibhedlele seTB sase-Empilweni? Amaziko ogcino-zidumbu eMpuma Koloni aye ancedwa njani ukuze ajongane nokusilela? Ngaba iinkqubo zomthetho bezilandelwa ngaphambi kokukhutshwa kwemizimba ukuze kuvavanyelwa i-Covid-19?

UMphathiswa wezeMpilo eNtshona Koloni ubhengeze ukuba iNtshona Koloni iphambili ekulawuleni ubhubhane. Inkqubo yethekhnoloji yeli phondo yaphuhliswa kakuhle ukulungiselela ukuququzelela ukuqokelelwa kwedatha kunye nokunika ingxelo yobuntlola yonke imihla. Nokusweleka ngaphandle kwenkqubo yezempilo kunokuvavanywa kuba inkqubo ijongiwe ngokuchasene nedatha yezeKhaya. Iphondo belisebenza nemibutho yabasebenzi kumgangatho wocwangciso kwaye oosodolophu boomasipala kwafuneka ukuba banike ingxelo ngedatha ye-Covid-19 kunye nokungenelela koomasipala babo. Isifundo esibaluleke kakhulu yayikukuba umntu akanako ukuqinisa inkqubo ngaphandle kokujongana nesidingo sabasebenzi bokhathalelo lwempilo kwaye benziwe baphambili kwiphondo. Iphondo leNtshona Koloni libongoze uMongameli ukuba abuphelise utywala iiveki ezimbini ngexesha leziyunguma zexesha leeholide zexesha leeholide zexesha leeholide zokuphela konyaka ukuze enze umoya wokuphefumla kwinani elixhaphakileyo leemeko zomothuko ezibangelwa butywala ngelo xesha.

INtloko yeSebe yathetha ngeSicwangciso esine-5-point COVID Resurgence Strategy saseNtshona Koloni esijolise ekutshintsheni indlela yokuziphatha yoluntu, ukubekwa kweliso kunye nokusabela, ukunyusa umthamo weenkonzo zempilo, ukugcina iinkonzo ezibanzi kunye nokukhusela abasebenzi bezempilo. Uthe iphondo lizakulenyusa njani iqonga lezempilo, lilawule ukubhubha kwabantu kwaye uchaze isicwangciso sogonyo sephondo. Zonke izithili zaseNtshona Koloni yayizezona ndawo ziphambili ngelo xesha, kodwa iGarden Route yayigqithile ngokucacileyo kwincopho yeliza lesibini kwaye yayikwindlela ehlayo. UNxweme oluseNtshona lubonise ukwanda kwamatyala, nto leyo ebonisa ukuba le ndawo ikwinqanaba elingaphambili le-wave lesibini kunezinye izithili. Eli phondo linenani elikhulu lezigulana ezinesifo seswekile ezazisemngciphekweni omkhulu wokungenwa ngulo bhubhani, kodwa amacebo afundiweyo malunga nendlela yokulawula isifo seswekile kwiliza lokuqala. Amayeza ayesiwa emakhayeni ukuze izigulane zingayi ezibhedlele ukuya kuthatha amayeza azo. Iphondo belixhalabile ngakumbi ngomonzakalo ofunyanwa ngabasebenzi bokhathalelo lwempilo olufuna ukuphiliswa ixesha elide.

Amalungu abuze ukuba ngawaphi amanyathelo athathwa yiNtshona Koloni ukujongana neengxaki ezinxulumene nesifo seswekile notywala; ukuba iSebe lezeMpilo liye lathetha neBhunga loLawulo lwePhondo malunga nezinga eliphantsi lokuthotyelwa kwephondo lokunxiba iimaski kunye nokungena eluntwini; kwaye beluthini uluvo lwephondo malunga nelizwe elihlawule izigidi ezingama-283 zeerandi kwisitofu sokugonya i-SAHPRA ingekaphunyezwa. Ilungu liqaphele ukuba abanye abasebenzi babika ukuba baphoqeleka ukuba baye emsebenzini nokuba bagula nje bengenazo iimpawu. Yayiyinyaniso kangakanani loo nto? Ngubani owayezalisa izithuba ezili-1029 zabasebenzi bezempilo ababegula? Iphondo belizimisele njani ukuvala umsantsa kumlinganiselo weoksijini osetyenziswa kuluntu xa kuthelekiswa necandelo labucala? Ngaba abaguli abavinjwe amathuba ngenxa yentlupheko abaxhomekeke kukhathalelo lwempilo yoluntu babenethuba elisezantsi lokufikelela kwi-oksijini? Ngaba i-Afrox yayikuphela komboneleli weoksijini kumanqanaba afunekayo? Kwenzeka ntoni ukuba i-Afrox ayikwazanga ukubonelela ngeoksijini eyaneleyo njengoko ioksijini yayilungenelelo olubalulekileyo?

Amalungu abuze ukuba ingaba iNtshona Koloni iyazi na ukuba kutheni izithili ezithwaxwe kakubi kwiliza lokuqala zingakhathazeki kangako kwiliza lesibini. Ngaba kukho izicwangciso zokwabiwa, ukuthutha kunye nokugcinwa kwesitofu sokugonya, kungekhona nje kwi-metro, kodwa nakwizithili? Besithini isicwangciso sokujongana neewadi ezigcweleyo zaseICU nanjengoko iphondo belingafuni zakhiwo zethutyana? Zeziphi iindawo ezibalulekileyo ezibe negalelo kwizinga eliphezulu lokufa kwabantu kwiphondo? Ngawaphi amanyathelo okungenelela aya kuqaliswa ukuphelisa loo mkhwa? Bekunxibelelana njani noluntu malunga nendlela yokujongana ne-Covid-19 ekhaya kunye nexesha lokufuna unyango? Ngaba isitofu sokugonya besokuzithandela okanye besisisinyanzelo kwaye ngaba oko kuya kwaziswa ngokucacileyo kwabo baza kufumana isitofu sokugonya?

Isishwankathelo sinikezelwe ngu IQela eliPhonononge iPalamente

I-Indiya ivume ezimbini (2) yenziwe eIndiya izitofu zokugonya – Oxford-AstraZeneca's 'Indawo yokuhlala' kunye neBharat Biotech'sCovaxin' kugunyaziso losetyenziso olungxamisekileyo. Nantsi into esiyaziyo malunga nokusebenza kwezi zitofu ukuza kuthi ga ngoku:

• Indawo yokuhlala

Olu gonyo luphuhliswe ngabakwa IYunivesithi yaseOxford kunye neBritish-Swedish inkampani yamachiza AstraZeneca. Adar Poonawalla, iGosa eliyiNtloko lesiGqeba, Iziko laseSerum laseIndiya (SII) - eyiBhritani-Swedish pharma giant AstraZeneca iqabane lemveliso – uthe isitofu sokugonya siya kuba I-90 ukuya kwi-95 yepesenti esebenzayo ukuba izithonga ezimbini zihlulwe malunga neenyanga ezi-2-3. “Uza kuva iindaba ezimnandi ezivela e-UK kwakamsinyane… Iyakuba yi-90-95% yesitofu sokugonya esisebenzayo ukuba ugcina umsantsa weenyanga ezimbini ukuya kwezintathu phakathi kwedosi yoku-1 kunye nedosi yesi-2. ngamaxwebhu.” I-Covishield, i-Poonawalla yongezwe, lugonyo olusebenzayo ngokuchasene ne-coronavirus entsha. Isitofu sokugonya sichazwa njengesinye sezitofu zokugonya ezithembisayo eIndiya apho iindleko kunye nolungiselelo lolungiselelo ludlala indima enkulu. Ngokucacileyo, ngokungafaniyo nogonyo lwePfizer kunye neModerna, ezisebenzisa indlela entsha ebizwa ngokuba yi-mRNA, izenza intsonkothe ​​ngakumbi, zibuthathaka kwaye zifuna kubanda kakhulu amaqondo obushushu, I-Covishield sisitofu sokugonya se-vector esicothayo kodwa esifikelelekayo kwaye okubalulekileyo, sinokugcinwa sizinzile kangangeenyanga ezintandathu kumaqondo obushushu aqhelekileyo efriji.

• Covaxin

I-Covaxin iphuhliswe yinkampani yebhayoloji yaseIndiya iBharat Biotech kunye nequmrhu lophando lwezonyango laseIndiya iBhunga loPhando lwezoNyango (ICMR). Ingxelo ye-NDTV ibiza i-Covaxin isitofu sokugonya esingasebenziyo - enye yeendlela zakudala zokugonya abantu - okuthetha ukuba iintsholongwane ezipheleleyo, ezingasebenziyo zitofwa emzimbeni ukuze kuphendulwe amajoni omzimba. Ezi bhetshi zizonke ze-coronavirus kufuneka zikhuliswe, "zibulawe" kusetyenziswa imichiza okanye ubushushu emva koko zenziwe isitofu sokugonya, oko kuyenza ibe yinkqubo ende, itsho ingxelo.  Covaxin Iifom zemvume zichaza ukuba abaxhamli baya kunikwa ukhathalelo kwizibhedlele ezichongiweyo nezigunyazisiweyo ngurhulumente ukuba kukho naziphi na iziphumo ebezingalindelekanga ezibi ngenxa yesitofu sokugonya, utshilo ingxelo yaseIndiya. Abaxhamli abafumana iCovaxin baya kuhlawulwa imbuyekezo ukuba bafumana ubunzima iziganeko ngenxa yesitofu sokugonya. Imbuyekezo yayiphakathi kwamanqaku agxininiswe phezulu kwifomu yemvume ekwabelwana ngayo neziko lokugonya ngoLwesihlanu. Ngokweengxelo, “ukusebenza ngonyango kwe-Covaxin kuseza kusekwa kwaye kuyaphononongwa kwisigaba sesi-3 solingo lwezonyango”.

INKCAZELO YE-SAHPRA YOKUSETYENZISWA KWE-IVERMECTIN KWI-PROPHYLAXIS OKANYE KUNYANGO LWE-COVID-19

Yintoni ivermectin?

Ivermectin lichiza elisetyenziswa ngokubanzi kunyango kunye nolawulo lwezifunxi-gazi kwizilwanyana kwaye isetyenziselwa ukunyanga izifo ezininzi zetropikhi ebantwini abaqhelekanga ukubonwa eMzantsi Afrika, kunye nokhwekhwe kunye neentwala zentloko. Ivermectin yimveliso eyenziweyo yeklasi ye-antiparasitic yeekhompawundi eyaziwa ngokuba yi-avermectins.

EMzantsi Afrika ivermectin ibhaliselwe ukusetyenziswa phantsi koMthetho wama-36 ka-1947 (iSebe lezoLimo) ukuze isetyenziswe kwizilwanyana. Oku kuthetha ukuba oogqirha bezilwanyana kunye nabanye abasebenzi abaqeqeshiweyo bavumelekile ukuba bayimisele njenge-arhente ye-antiparasite yeentlobo zezilwanyana. Ichiza okwangoku alibhaliswanga ukuba lisetyenziswe ngabantu, kodwa i-SAHPRA ngamanye amaxesha inika iimvume zeCandelo lama-21 ukuze kusetyenziswe i-ivermectin esentloko njengemveliso engabhaliswanga kunyango lwezigulane ezineemeko ezifana nokhwekhwe okanye iintwala zentloko.

Abaphandi abaliqela baye baxela ukuba xa kuvavanywa elabhoratri, i-ivermectin inqanda ukuphindaphinda kwe-acute acute breathing syndrome i-coronavirus 2 (SARS-CoV-2). Xa kujongwa ubhubhani we-coronavirus (COVID-19) okhoyo ngoku, ngokuqondakalayo oku kufumene ingqalelo enkulu kumajelo eendaba. Ke, izifundo ezininzi zeklinikhi zenziwe ukuvavanya ukusebenza kwe-ivermectin ekunyangeni usulelo lwe-COVID-19.

Kwamanye amazwe apho i-ivermectin ibhaliselwe ukusetyenziswa ngabantu, ukuqulunqwa kokusetyenziswa komntu kusetyenziswa ngaphandle kweleyibhile kulawulo losulelo lwe-Covid-19 apho uxanduva lweklinikhi lokubeka iliso kukhuseleko kunye nokusebenza lulele kuphela kummiselo. Ngaphaya koko, kukho iingxelo ezixhaphakileyo zokusetyenziswa kwe-ivermectin kwiprophylaxis okanye unyango lwe-COVID-19 eMzantsi Afrika kusetyenziswa imveliso yonyango lwezilwanyana.

Uluvo lwe-SAHPRA malunga nokusetyenziswa kwe-ivermectin luchazwe ngoDisemba ka-2020

Ngomhla wama-22 kuDisemba 2020, i-SAHPRA yabonisa ukuba ngokunxulumene nokusetyenziswa kwe-ivermectin kwi-COVID-19, ukuba “Ivermectin ayiboniswanga kwaye ayivunywanga yi-SAHPRA ukuba isetyenziswe ebantwini. Akukho datha iqinisekisayo kwi-ivermectin ekhoyo okwangoku yokusetyenziswa kwayo kulawulo losulelo lwe-COVID-19. Ngokuphathelele ukhuseleko kunye nokusebenza kakuhle akukho bungqina bokuxhasa ukusetyenziswa kwe-ivermectin kwaye asinabo nabuphi na ubungqina bovavanyo lweklinikhi ukuthethelela ukusetyenziswa kwayo.

ULuhlu lwaMayeza aBalulekileyo (EML) Ikomitana ye-COVID-19 uPhononongo oluKhawulezayo kwi-ivermectin (nge-21 kaDisemba 2020)

I-SAHPRA ikwaqaphela ukuba iKomitana ye-EML COVID-19 ipapashe uPhononongo oluKhawulezayo kwi-ivermectin (nge-21 kaDisemba2020) apho bagqibe ngelithi:

• Umgangatho uwonke wolingo olungenamkhethe olubandakanya ivermectin kwizigulana ze-COVID-19 uphantsi kakhulu.
• Ukususela kubungqina bovavanyo olukhoyo olukhoyo, i-ivermectin ayikho phezulu kune-placebo ngokwemiqathango yokunciphisa umthamo wentsholongwane okanye ukuqhubela phambili kweklinikhi. Akukho bungqina obuvela kulingo lolawulo olungenamkhethe kuko nakuphi na ukuncitshiswa kokusweleka.

Izigulana ezifanelekileyo ezine-COVID-19 eMzantsi Afrika kufuneka ziqwalaselwe ukuba zibhalise kulingo olufanelekileyo lonyango.

Uphononongo lwe-SAHPRA lwedatha yangoku yokusetyenziswa kwe-ivermectin kunyango okanye iprophylaxis yosulelo lwe-COVID-19

Ukuphendula kulo mdla ukhulayo we-ivermectin kunye nesixa esikhulayo sedatha yokusetyenziswa kwayo kunyango lwe-COVID-19 kunye nothintelo, i-SAHPRA ngoku iye yaphonononga kwakhona, idatha ekhoyo evela kwizifundo zeklinikhi.

Uhlalutyo lwamva nje lwemeta, oko kukuthi uphononongo olucwangcisiweyo, lwedatha yolingo lwezonyango kunyango lwe-COVID-19 lwenziwe nguGqr Andrew Hill weYunivesithi yaseLiverpool, exhaswa yi-Unitaid elinyathelo lezempilo lehlabathi elisebenza kunye namaqabane ukuzisa. malunga nokwenziwa kwezinto ezintsha zokuthintela, ukuxilonga nokunyanga izifo ezikhulu kumazwe anengeniso ephantsi naphakathi). Nangona le ngxelo ifumaneka ngokubanzi esidlangalaleni, ayikapapashwa kwijenali yenzululwazi ephononongwe ngoontanga.

Uhlalutyo lwe-meta lugqibe kwelokuba ukusetyenziswa kwe-ivermectin kulawulo losulelo lwe-COVID-19 inxulunyaniswa nexesha elikhawulezayo lokucocwa kwentsholongwane, ixesha elifutshane lokulaliswa esibhedlele kunye namazinga aphezulu okuchacha kweklinikhi kunye nophuculo oluthile kumazinga okusinda.

Nangona kunjalo, uhlalutyo lwe-meta lukwaqukumbele ukuba idatha eyongezelelweyo yolingo lweklinikhi iyafuneka ukuze kuqinisekiswe inzuzo yeklinikhi kusulelo lwe-COVID-19 kunye nokuchaza irejimeni yedosi ephuculweyo. Ngaphaya koko, uGqr Hill uchonge inani lemida kwidatha evela kolu lingo lwezonyango, kubandakanya oku:

• Iziphumo zangoku zisekwe kulingo oluqingqiweyo olungakhethiyo
• Kukho ukuthambekela kokupapasha okunokwenzeka
• Ulingo lomntu ngamnye olujongiweyo lwalunamandla alinganiselweyo ezibalo
• Amalingo aliqela ayeneleyibhile evulekileyo ebonisa ukubanakho ukuthambekela komphandi
• Uluhlu lweedosi kunye nobude bexesha aluzange lubekwe emgangathweni
• Iingongoma zokuphela zahlukile phakathi kwezilingo

Kwisiphelo sakhe, uGqr Hill ubonise ukuba iimvavanyo zeklinikhi eziyilwe kakuhle ziyafuneka ukubonelela ngedatha yesayensi eyaneleyo ukuze kusetyenziswe i-ivermectin kunyango lwe-COVID-19.

Ngokusekwe kuhlalutyo lwemeta ye-Hill kunye ne-Front Line COVID-19 Critical Care Alliance (FLCCC), i-SAHPRA iqaphela oku kulandelayo:

• Umgangatho uwonke wolingo lweklinikhi olungacwangciswanga olubandakanya i-ivermectin kwizigulana ze-COVID-19 ulambatha kwaye awunamandla. Ukususela kubungqina bovavanyo olukhoyo olukhoyo, ivermectin ibonakala ingekho ngaphezu kwe-placebo ngokwemiqathango yokunciphisa umthamo wentsholongwane okanye ukuqhubela phambili kwekliniki. Akukho bungqina obuvela kwizilingo ezilawulwa ngokungenamkhethe kuko nakuphi na ukuncitshiswa kokusweleka.
• Uphononongo luyahluka ngokubhekiselele kumaqela abantu ababandakanyiweyo kuphononongo okt izigulane ezingalaliswanga, ukulaliswa esibhedlele kwangoko, izigulane ezilaliswe ixesha elide esibhedlele, izigulane ezikwi-ICU njl.njl.
• Iidosi kwizifundo ezahlukeneyo azifani. Ngenxa yoko, ukufumana idosi akunakumiselwa kulawulo olukhuselekileyo nolusebenzayo losulelo lwe-COVID-19 (nokuba lolonyango okanye lokuthintela).
• I-Ivermectin iye yavavanywa kunye namanye amayeza ahamba kunye (angqiniwe kwaye angaqinisekiswanga, nokuba yodwa okanye edityaniswe namanye amayeza) kwaye oku kunciphisa izigqibo ezinokuthi zenziwe malunga nokhuseleko lwe-ivermectin kunye nokusebenza kakuhle.
• Ezi zifundo zinemida eyongezelelweyo echongwe ngababuyekezi ngokwabo njengoko kuboniswe ngasentla, eyona nto iphawulekayo kukuba akukho datha yelingo eyaneleyo ekhoyo ngoku. Kodwa kuqatshelwe ukuba kuyakubakho idatha eyongezelelweyo yezonyango ekhoyo phakathi ukuya ekupheleni kukaJanuwari ka-2021. I-SAHPRA ilulindele ngolangazelelo olu lwazi ukuze ihlole isimo sayo sokusetyenziswa kwe-ivermectin kulawulo losulelo lwe-Covid-19.

I-SAHPRA iphawula ukuba ukuza kuthi ga ngoku, akukabikho zindululo zilungileyo zokusetyenziswa kwe-ivermectin kulawulo losulelo lwe-Covid-19 lilo naliphi na igunya elilawulayo apho i-SAHPRA inezivumelwano zokuthembela kuye, umz. USFDA, EMA, MHRA, njl., kunye nokuba i-WHO ayikukhuthazi okwangoku ukusetyenziswa kwe-ivermectin kunyango okanye iprophylaxis yosulelo lwe-COVID-19.

Ngaphaya koko, ingxelo kwi-pharmacokinetics ye-ivermectin yagqiba kwelokuba 'iziphumo zokuqala zibonisa ukuba iidosi eziqhelekileyo ze-ivermectin aziyi kukhokelela kugxininiso olusebenzayo, kwaye iidosi ezingaqhelekanga zokufikelela ukugxila okusebenzayo zinokukhokelela kwityhefu engamkelekanga kwizigulana ze-COVID-19.' (Ref: Pharmacometrics Afrika kunye ne-CERTARA).

Kwakhona kubalulekile ukuqaphela ukuba ngelixa i-ivermectin ithathwa njengekhuselekile ngokubanzi, iziphumo ebezingalindelekanga ziquka ukuqhambuka kwesikhumba, isicaphucaphu, ukuhlanza, urhudo, iintlungu zesisu, ubuso okanye ukuvuvukala kwelungu lomzimba, iimeko ezingathandekiyo ze-neurologic (isiyezi, ukuxhuzula, kunye nokudideka), ukuhla ngokukhawuleza. uxinzelelo lwegazi, irhashalala ebukhali eluswini enokuthi ifune ukulaliswa esibhedlele kunye nokwenzakala kwesibindi (ihepatitis). Iziphene zovavanyo lwaselabhoratri ziquka ukuhla kwenani leeseli ezimhlophe kunye novavanyo oluphezulu lwesibindi.

Ubume bangoku bezicelo kwi-SAHPRA zokwamkelwa kolingo lwezonyango okanye ukubhaliswa

Okwangoku, akukho zicelo zolingo lwezonyango lwe-ivermectin eziye zathunyelwa kwi-SAHPRA ukuze zihlolwe. I-SAHPRA ikhuthaza ukungeniswa kwezicelo zolingo lwezonyango eziyilelwe ukuseka ukhuseleko nokusebenza kwe-ivermectin kulawulo losulelo lwe-Covid-19 kunyango kunye ne-prophylaxis kwaye izibophelele ekukhawuleziseni uphononongo lwazo. Le ndlela ngaphambili ibisetyenziswa kwizicelo zolingo lwezonyango kwamanye amayeza ophando ebevavanyelwa ulawulo lwe-COVID-19.

Ukongeza, i-SAHPRA ayifumananga zicelo zokubhalisa i-ivermectin mhlawumbi ye-prophylaxis okanye unyango lwe-COVID-19 kodwa izibophelele ekukhawuleziseni uphononongo lwaso nasiphi na isicelo esinjalo ukuba singenisiwe.

isiphelo

Okwangoku akukho zicelo nokuba zezolingo lwezonyango okanye zobhaliso lwe-ivermectin kunyango okanye njenge-prophylaxis ye-COVID-19. Nangona kunjalo, i-SAHPRA ikhuthaza kwaye ixhasa zonke izifundo eziyilwe kakuhle, ezivunyiweyo ngokweenqobo zokuziphatha, ezenzelwe ukuchonga amayeza amatsha okanye asele ekhona asetyenziselwa unyango okanye ukuthintela i-COVID-19. I-SAHPRA iyakuphinda ukuzinikela kwayo ekukhawuleziseni uphononongo lophononongo olunjalo. Ngaphaya koko, njengogunyaziwe olawulayo waseMzantsi Afrika, i-SAHPRA iya kuqhubeka nokuvavanya naluphi na upapasho oluphononongwe ngabalingane abasakhulayo okanye idatha ngokusetyenziswa kwe-ivermectin kunyango lwe-COVID-19, kwaye iqaphela ukuba ngokwerejista yolingo lwezonyango lwehlabathi, idatha eyongezelelweyo kufuneka ifumaneke. ekuhambeni kweenyanga ezimbalwa ezizayo. I-SAHPRA iya kuphinda ithathele ingqalelo ukuvumela ukufikelela kwimixube evunyiweyo ye-ivermectin ejoliswe ekusetyenzisweni komntu, kubandakanywa nesigunyaziso seCandelo lama-21, ngaphandle kokuba isicelo esinjalo sixhaswa bubungqina besalathiso esiceliweyo kwaye siyathetheleleka ngokusekelwe kuvavanyo lwenzuzo yomngcipheko olubandakanya ukhuseleko kunye neenkcukacha zeklinikhi. .